DMT is a psychedelic tryptamine. It is an indole alkaloid and has a chemical structure similar to the neurotransmitter serotonin. This similarity in structure between DMT and serotonin allows it to bind to serotonin receptors. Specifically DMT acts as an agonist of the 5-HT2A receptor, whereby it binds and stimulates a response. It is thought that 5-HT2A receptor agonism plays a major role in the hallucinogenic effects of DMT. The 5-HT2A receptor is associated with several other classical psychedelics, including psilocybin and LSD, and consequently these psychedelics can often be referred to as serotonergic psychedelics.
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Psychological effects
DMT is rapidly acting and effects are typically observed around 2-5 minutes after consumption and last around 15-20 minutes. Despite its short-lived effects, DMT is known as one of the most powerful psychedelic drugs. The subjective effects of DMT can often be meaningful but will vary with dosage. These include:
- Eliciting intense visual alterations and hallucinations, specifically colourful and geometric forms
- Profound spiritual or mystical experiences
- Varying alternations in mood and emotion, including experiences of euphoria, calm, fear and anxiety
- Perceived encounters with external entities, which are often described as elf-like.
- Altered sense of time and place
- A sense of depersonalisation or out of body experiences
- Potential auditory hallucinations
- Evocation of powerful memories
Physiological effects
DMT is associated with low toxicity and is easily metabolised by the body. However, there are physiological implications and associated risks to be aware of. These include elevated blood pressure and increased heart rate, which is particularly risky for those with heart conditions. The impaired cognitive and motor function poses a personal safety risk and presents further reason for DMT to be consumed in a safe environment with a sober sitter. It should be noted that at high doses there are some reports of seizures, respiratory effects and comas.buy dmt online
Dosage
| Vapourised | |
|---|---|
| Threshold | 5-10mg |
| Light | 10-15mg |
| Common | 15-25mg |
| Strong | 25-35mg |
| Heavy | 35mg+ |
| Insufflated | |
|---|---|
| Light | 10-25mg |
| Common | 25-50mg |
| Strong | 50-125mg+ |
| Intravenous | |
|---|---|
| Light | 10-15mg |
| Common | 15-25mg |
| Strong | 25-40mg |
Duration
| Vaporized/smoked | |
|---|---|
| Onset | 0-2 minutes |
| Duration | 3-10 minutes |
| After-effects | 15-60 minutes |
| Oral_MAOI | |
|---|---|
| Onset | 20-45 minutes |
| Duration | 180-420 minutes |
| After-effects | 15-60 minutes |
| Insufflated | |
|---|---|
| Onset | 3-5 minutes |
| Duration | 45-60 minutes |
| After-effects | 15-60 minutes |
Risk
Physical health risks
Lots of indigenous peoples in South America use drinks or food that contain DMT as part of their culture – the best known example is ayahuasca ceremonies.dmt powder for sale
For this reason, some people think DMT is spiritual and therefore safe, but it is still a chemical hallucinogen.
This means it can:
- raise your blood pressure
- raise your heart rate
- be harmful to those with a pre-existing heart condition
- cause nausea and vomiting, as a result of intoxication
Mental health risks
DMT can produce very unpredictable – and sometimes very frightening – effects, which feed off a person’s imagination.
If panic sets in, the experience can be scary and confusing.
Taking a hallucinogen like DMT can:
- Lead to flashbacks, this is when part of the trip is subsequently relived after the original experience.
- Be especially serious for someone with a history of mental health problems. It could trigger a problem for someone who didn’t know they had a predisposition to mental health problems.
- Lead to the user harming him or herself if the trip goes bad – so it’s probably best to avoid taking DMT if you’re in a bad or anxious mood.
- Lead to unpleasant and emotional effects that could last for days after taking the drug.buy dmt online
